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OXIDATIVE STRESS AND DISEASES

  

THE SEARCH FOR A CURE-ALL PRODUCT  - OXIDATIVE STRESS TO THE RESCUE

THE AMAZING POWERS OF JOBELYN

 Regular Jobelyn Packs

For centuries the people of South-Western Nigeria depended on a herbal extract to cure diseases of diverse origin, including Anemia, Sickle Cell Anemia, Arthritis, Stroke, Hypertension, Diabetes, Infertility, Malaria, Cardiovascular diseases, HIV/AIDS, Leukemia, Multiple Myeloma, Breast Cancer, Hodgkin’s Lymphoma, Lupus, neurological diseases etc. This remedy was handed over by their forefathers from generation to generation. Scientists would ordinarily dismiss this claim as it was difficult to substantiate with credible evidence. The main ingredient for the preparation of this medicinal product is the special Sorghum bicolor leaf sheath which is only available at a particular location in Nigeria.

It has taken more than 20 years to unravel the mystery behind this miraculous herbal remedy. I had a strong resolve to pursue this mystery scientifically and only in recent times I am having a clue that would be accepted as credible. In the series of blogs that would follow, I will explain the various stages of the development of this product and show how almost all diseases have a common factor known as OXIDATIVE STRESS.

 

WHAT IS OXIDATIVE STRESS?

 

Oxidative stress is defined as a disturbance in the balance between the production of reactive oxygen species (free radicals) and antioxidant defenses

Oxidative stress happens when the pro-oxidants are in excess of anti-oxidants and the destruction of human cells lays the foundation for the development of all diseases like Anemia, Anemia, Sickle Cell Anemia, Arthritis, Stroke, Hypertension, Diabetes, Infertility, Malaria, Cardiovascular diseases, HIV/AIDS, Leukemia, Multiple Myeloma, Breast Cancer, Hodgkin’s Lymphoma, Lupus, neurological diseases etc.

Oxidative Stress (OS) is a general term used to describe the steady state level of oxidative damage in a cell, tissue, or organ, caused by thereactive oxygen species(ROS). This damage can affect a specific molecule or the entire organism. Reactive oxygen species, such as free radicals and peroxides, represent a class of molecules that are derived from the metabolism of oxygen and exist inherently in all aerobic organisms.

 

There are several sources by which the reactive oxygen species are generated. Most reactive oxygen species come from the endogenous sources as by-products of normal and essential metabolic reactions, such as energy generation from mitochondria or the detoxification reactions involving theliver cytochrome P-450 enzyme system. Exogenous sources include exposure to cigarette smoke, environmental pollutants such as emission from automobiles and industries, consumption of alcohol in excess, asbestos, exposure to ionizing radiation, and bacterial, fungal or viral infections.

The level of oxidative stress is determined by the balance between the rate at which oxidative damage is induced (input) and the rate at which it is efficiently repaired and removed (output). The rate at which damage is caused is determined by how fast the reactive oxygen species are generated and then inactivated by endogenous defense agents called antioxidants. The rate at which damage is removed is dependent on the level of repair enzymes.

The determinants of oxidative stress are regulated by an individual's unique hereditary factors, as well as his/her environment and characteristic lifestyle. Unfortunately, under the present day life-style conditions many people run an abnormally high level of oxidative stress that could increase their probability of early incidence of decline in optimum body functions.

Your body constantly reacts with oxygen as you breathe and your cells produce energy. As a consequence of this activity, highly reactive molecules are produced known as free radicals.

Free radicals interact with other molecules within cells. This can cause oxidative damage to proteins, membranes and genes.

 

Oxidative damage has been implicated in the cause of many diseases, such as cancer and Alzheimer's and has an impact on the body's aging process.

External factors, such as pollution, sunlight and smoking, also trigger the production of free radicals.

 

Antioxidants:

 

Working to protect the body on a cellular level

 

To counteract oxidative stress, the body produces an armoury of antioxidants to defend itself. It's the job of antioxidants to neutralise or 'mop up' free radicals that can harm our cells.

Your body's ability to produce antioxidants (its metabolic process) is controlled by your genetic makeup and influenced by your exposure to environmental factors, such as diet and smoking.

Changes in our lifestyles, which include more environmental pollution and less quality in our diets, mean that we are exposed to more free radicals than ever before.

 

Oxidation.

 

We know it’s a bad thing for the body, and doctors tell us to eat lots of antioxidant fruits and vegetables. But how does oxidation happen anyway?

We need oxygen for life. Our lungs take it in, and a complex network of capillaries and alveoli enable red blood cells to acquire the oxygen and deliver it throughout the body. But, as oxygen is used in various processes, tiny electrons can break off. These unpaired electrons are called free radicals. Think of them as the waste product of cellular processes.

There are some processes where free radicals are actually a good thing – for instance, to kill bad bacteria in certain immune system functions. But, generally free radicals are not helpful. They bounce around hitting cells and causing damage, sometimes even breaking off portions of DNA. The grand sum of this cellular damage is at the root of many health conditions including cardiovascular challenges, poor immune response, and even the appearance of wrinkles on the skin. This is the cumulative wear and tear that results from simply living life. Oxidation is also aggravated by stress, environmental factors, and poor diet.

The effects can be tempered though, through a diet and supplement program rich in antioxidants. Just like it sounds, an antioxidant is a substance that naturally combats oxidation. Antioxidants are substances that bind up the stray electrons and render them harmless. Antioxidant foods and dietary supplements are rated using the ORAC scale, which is a measure of the substance’s ability to absorb free radicals. When compared to other recommended antioxidant foods, Jobelyn boasts one of the highest food-source ORAC ratings known. That makes it a superior choice for antioxidant supplementation.

 

Applying the Science:

 

How Sorghum bicolor leaf extract helps specific conditions

 

 

Blood Cell Health 

 

Jobelyn provides strong antioxidant support for red blood cells. Understanding the oxidation process, it’s easy to see how red blood cells might be particularly vulnerable to the damaging effects of oxygen radicals. Red blood cells are the body’s oxygen carriers. In the course of their 120-day lifespan, they are constantly in contact with this double-edged sword – the element that we require for life, which is also the origin of oxidation. Adding to the challenge is the fact that mature red blood cells do not have a nucleus, so they cannot produce new proteins in response to oxidative damage. One way to support red blood cell health is to prevent oxidation through strong antioxidant supplementation.

 

Antioxidant supplementation is especially important for people whose red blood cell health is compromised due to anemia, including Sickle Cell Disease. Recent scientific studies have looked specifically at the effects of Jobelyn on anemia and found that it effectively increases packed cell volume (PCV – the sheer number of blood cells) and hemoglobin concentration (Hb – an indicator of red blood cell health). Preliminary human clinical research in Nigeria has confirmed these results, showing some beneficial effects after just a week of supplementation and significant improvements for 102 of 113 patients after 6 weeks.8

 

In the case of Sickle Cell Disease, not only does Jobelyn help in its antioxidant activity, but its anti-inflammatory properties may be of benefit too. Some researchers believe that sickle red cells can provoke inflammation throughout the circulatory system because the deformed cells physically hinder smooth blood flow. Jobelyn works both at the level of protecting the red blood cells from oxidation and on the level of protecting the circulatory system from the inflammation state that can create even more free radicals. This herbal remedy cuts off the cycle of oxidation and inflammation that aggravates sickle cells. While it can’t cure the physical shape and structure of the sickle cells, it can lessen the damage and effects of the cell deformity.

 

Cardiovascular Health

 

Seeing how helpful Jobelyn is for the stressed circulatory system in Sickle Cell Disease patients, it’s a small step to recognize how helpful it is for cardiovascular health in general. The medical community now views free radical oxidation and ongoing inflammation as primary contributors to heart disease, cholesterol build-up, and arteriosclerosis (severe thickening and hardening of artery walls).

Just as red blood cells are exposed to lots of free radicals, so are heart and blood vessel cells. Heart cells also have the added stress of being involved in constant contraction. This muscle activity produces plenty of free radicals as a byproduct. Antioxidant protection is vital for the cardiovascular system.

Not only do antioxidants prevent damage to individual cells, they can also prevent the breakdown of nitric oxide (NO). NO is a gas naturally produced in the cardiovascular system, which helps promote relaxation and expansion of the blood vessels. By supporting NO, antioxidant supplementation can enhance blood flow. This explains why Jobelyn has been found to enhance circulation.

The cardiovascular system also benefits from Jobelyn’s anti-inflammatory effects. Fatty plaque build-up in blood vessels often occurs due to low-grade inflammation and irritation throughout the vessel walls. This inflammation makes it easier for cholesterol particles to stick to the lining of the blood vessels. Reducing inflammation can actually lower the incidence of atherosclerosis (fatty plaque deposits) and coronary events.

 

 

Joint Health

 

 Just as oxidation and inflammation are at the core of blood cell and cardiovascular health threats, this troublesome duo is also involved in causing joint degeneration and pain. The intricate connective tissue and surfaces of our joints are under constant challenge from daily use. Ongoing wear and tear, along with occasional injury, result in plenty of free radical production and inflammation. Without antioxidant support and balancing of the inflammation process, the result can be achy joints and limited range of motion.

We’ve touched on the role of Jobelyn as a powerful antioxidant and a very selective COX-2 inhibitor. Jobelyn has also demonstrated an ability to inhibit the release of pro-inflammatory proteins called cytokines. We learned how the combination of anti-inflammatory and antioxidant support results in dramatic improvements for the cardiovascular system. The same benefits can improve joint health too.

In the joints, inflammation and oxidation create a self-reinforcing cycle. Inflammation creates oxygen free radicals as a byproduct, which can in turn cause more damage, which creates more inflammation, and so the cycle goes. Sorghum leaf sheath extract, which provides both antioxidant and anti-inflammatory effects, has been found to bring a dynamic end to this cycle.

 

A reduction in inflammation and pain means more range of motion and the freedom to work the joint and build strength. Strength-building through physical therapy helps prevent future injury. By ending a damaging pain cycle, Jobelyn has been found to begin a positive cycle of improving joint health especially when combined with an appropriate exercise program.

 

Immune System Response 

 

It takes a little more explanation to understand how Jobelyn supports the immune system. As with the case of red blood cell health, we need to drop down to a cellular and molecular level and think very small. It’s the antioxidant activity that is most vital for immune system support. Specifically, the extract provides components for the body to build its own super antioxidant: glutathione peroxidase.

The body creates glutathione and uses it for several protective tasks including protecting certain immune system cells called CD4 T-lymphocytes. Glutathione contains selenium and three amino acids (cystein, glutamine, and tryptophan). Jobelyn contains all three of these amino acids, providing the body with some major building blocks of glutathione.

 

Scientists believe this explains some astounding research coming out of Africa right now. In a preliminary human clinical study involving HIV-positive patients, Jobelyn supplementation improved compromised CD4 cell counts (30-300/1) by 200-300%. Those with initial CD4 counts greater than 300 also saw an increase of 20-30%. The increase in cellular immunity occurred regardless of whether the patient was taking other antiretroviral drugs.

 

Jobelyn is incredibly beneficial for the immune system when the body is under one of the heaviest attacks imaginable. It makes sense that the herbal would be helpful as a general immune system boost for anyone in fine health. Its effects appear to be moderated too; meaning it won’t make the immune system become overactive. That’s why we see such a dramatic increase for those with very compromised CD4 counts and a moderated increase for those who had higher initial counts. So, Jobelyn is a safe immune support supplement whether you’re looking for a little extra help during cold and flu season, or if you’re facing a much more daunting immune system challenge.

 

We have researched to find scientific evidence to support the role of oxidative stress in many diseases to buttress the assertion that Jobelyn, being one of the most powerful natural antioxidants has a prominent role to play in maintaining wellness and treating of many diseases.

We present to you a book that dealt exhaustively with this subject matter and hope you will enjoy reading through it.

Oxidative Stress and Diseases

 

Edited by Volodymyr I. Lushchak and Dmytro V. Gospodaryov, ISBN 978-953-51-0552-7, 624 pages, Publisher: InTech, Chapters published April 25, 2012 under CC BY 3.0 license
DOI: 10.5772/2535
Edited Volume

The development of hypothesis of oxidative stress in the 1980s stimulated the interest of biological and biomedical sciences that extends to this day. The contributions in this book provide the reader with the knowledge accumulated to date on the involvement of reactive oxygen species in different pathologies in humans and animals. The chapters are organized into sections based on specific groups of pathologies such as cardiovascular diseases, diabetes, cancer, neuronal, hormonal, and systemic ones. A special section highlights potential of antioxidants to protect organisms against deleterious effects of reactive species. This book should appeal to many researchers, who should find its information useful for advancing their fields.

 

 

 

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Healthy blood guarantees healthy body

How and why we need to keep our blood healthy

b2ap3_thumbnail_IMG_8794.JPGBlood is life. Blood in the human body is the equivalent of engine oil in a motor vehicle. Just like the vehicle engine oil, our blood has three main functions: transportation, regulation and protection.

Our erythrocytes, or red blood cells, are the most abundant cell type in the human body. Additionally, erythrocytes are anucleated, which means they don’t have a nucleus. This extra room allows for more haemoglobin to be stored in our red blood cells. Haemoglobin is a respiratory pigment, which binds to either oxygen or carbon dioxide. This allows oxygen to be transported around our body to our tissues and organs (and carbon dioxide to be taken away).

Blood also helps us to maintain homeostasis by regulating our internal body pH and temperature as well as how much water is in our bodies at a given time. Plasma, our connective tissue matrix, is about 90 percent water. Thus, the crucial importance of healthy blood cells cannot be over-emphasised as it is vital in protecting our bodies.

Haemoglobin is the protein inside red blood cells that carries oxygen. Red blood cells also remove carbon dioxide from your body, transporting it to the lungs for you to exhale. Foods rich in iron help us maintain healthy red blood cells. Vitamins are also necessary to build healthy red blood cells. These include vitamin E, found in foods such as dark green vegetables, nuts and seeds, mango, and avocados; vitamins B2, B12, and B3, found in foods such as eggs, whole grains, and bananas; and folate, available in fortified cereals, dried beans and lentils, orange juice, and green leafy vegetables.

Most people don’t think about their red blood cells unless they have a disease that affects these cells. Problems with red blood cells can be caused by illnesses or a lack of iron or vitamins in your diet. Some diseases of the red blood cells are inherited.

Diseases of the red blood cells include many types of anemia, a condition in which the body can’t produce enough normal red blood cells to carry sufficient oxygen throughout the body. People with anemia may have red blood cells that have an unusual shape or that look normal, larger than normal, or smaller than normal.

Symptoms of anemia include tiredness, irregular heartbeats, pale skin, feeling cold, and, in severe cases, heart failure. Children who don’t have enough healthy red blood cells grow and develop more slowly than other children. These symptoms demonstrate how important red blood cells are to your daily life.

In the past two decades, extensive research carried out by top scientists in the world have concluded that the inability of blood to fully perform its function and be healthy gives rise to Oxidative stress which has now been found to be the root cause of a wide range of ailments and diseases.

Oxidative stress (often called OS) is what happens when the body does not have enough antioxidants to neutralise free radicals. Free radicals are the unstable molecules that react with other substances in our body to damage cells or create abnormal ones. Overproduction of free radicals can cause oxidative damage to biomolecules, (lipids, proteins, DNA), eventually leading to many chronic diseases such as atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke, hypertension, diabetes, and kidney disease. Toxicity of free radicals also contributes to proteins and DNA injury, inflammation, tissue damage and subsequent cellular apoptosis.

Antioxidants are now being looked upon as effective therapy against these diseases, as they have capability to combat by neutralising free radicals. Diet is major source of antioxidants, as well as medicinal herbs. Recognition of upstream and downstream antioxidant therapy to oxidative stress has been proven to be an effective tool in alteration of any damage as well as free radical scavenging. Antioxidants have a wide scope to sequester and scavenge these free radicals to prevent oxidative stress.

 Jobelyn occupies a unique and remarkable position in the world of the combination of food and medicine. Laboratory analysis from the reputable GMP Laboratory of USA confirmed that Jobelyn contains Carbohydrates, Protein, Dietary Fibre, Iron which could be classified as food. In addition, it contains other nutrients which could be classified as medicine/food/amino acids and these include selenium, manganese, potassium, zinc, calcium, vitamins like A, B12, C, Omegas 3, 6 & 9, calcium and more. It is a well-known fact that doctors now prescribe multivitamins in addition to drugs. Jobelyn is rich in vitamins and other essential fatty acids and amino acids which are by far superior to the synthetic ones in the market and this is a compelling reason why doctors should prescribe it.

Jobelyn was developed from Sorghum bicolor leaf sheaths, which had been in use as folk medicine for centuries by natives of South Western Nigeria for the treatment of diseases of diverse origin including cancer, diabetes, sickle cell anemia, anemia, arthritis,  heart and liver diseases as well as HIV/AIDS. Health Forever Product Limited has spent the past 20 years to scientifically and clinically validate the proof in the positive use of these herbs by the natives to convince scientists and doctors that indeed, this folk medicine is capable of solving a variety of health problems.

Research, clinical and laboratory studies have been carried out in many institutions such as Lagos State University Teaching Hospital (LASUTH), Lagos University Teaching Hospital (LUTH), Obafemi Awolowo University Ile-Ife (OAU), Vivacell Laboratory, (Germany) Brunswick Laboratory (USA), MD Biosciences (USA), Texas AM University (USA), Natural Immune System (NIS) Laboratory (USA), Alcorn State University (USA)University College Ibadan (UI), University of Benin (UNIBEN), GMP Laboratories (USA), PhytoLabs (GERMANY), Military Hospital Ikoyi, Lagos and Police Hospital, Falomo, Lagos.

Human clinical trials have been done for sickle-cell anemia, anemia in pre-operative gynecological patients, HIV Studies in human and some of the results have been published in reputable journals. In vitro studies have been done to establish the antioxidant, anti-inflammatory properties of Jobelyn and the results have been published in peer-reviewed journals. In vivo animal studies have been carried out to show the potential of Jobelyn for restoring anemia and extensive in vivo studies were also carried out to establish the power of Jobelyn in neuro-cognitive deficits covering key areas like, stress, psychosis, dementia, schizophrenia, Alzheimer, seizure, depression, aggression, etc. The extensive work done on Jobelyn at Brunswick Laboratory has established that Jobelyn is the most powerful natural antioxidant in the world and the report has been published in a reputable journal. The safety of Jobelyn has been established through animal studies and in some of the human clinical trials carried out.

Being a most powerful and natural antioxidant, Jobelyn has consistently over the years proven to be a very effective means of combating oxidative stress and producing and restoring health blood cell into the body.

Advantages and uniqueness of Jobelyn to your health:

  • Solid Evidence based and unparalleled continuous scientific research of a made- in-Nigeria phyto (herbal) medicine
  • The most powerful natural antioxidant at 37,622 orac value,
  • Unmatched anti-chronic inflammatory agent – proven to be significantly, if not totally better than ibuprofen
  • Jobelyn induces production of very special cytokines like gcsf, gmcsf, CCl3, CCl4, etc. From immune cells to enhance the immune system.
  • Activator of natural killer t-lymphocytes
  • Scientifically, medically, and user based confirmed red blood cell protector and enhancer
  • Astounding and highly positively effective results when included in the management of hiv/aids and sickle cell disease.
  • Jobelyn crosses the blood brain barrier to express its cns effects, as seen in many studies.

Jobelyn is one of the most researched Traditional medicinal products in the whole world. From 1996 to date, Health Forever Product, Ltd., has continued to accumulate resources in terms of science based as well as long-term usage evidence for the efficacy of this most powerful African herbal formula which has its origin in the folk medicine of South Western Nigeria.

There is no doubt that Jobelyn, based on scientific evidence as well as usage evidence and testimonials, has proven to be at the front line in battling oxidative stress and restoring healthy blood to the body. Since oxidative stress is a regular occurrence in the body system, a regular consumption of powerful antioxidant like Jobelyn would undoubtedly protect the blood cells and also reduce the incidence of anemia.

A good blood system would support a good  immune system and  promote general well–being and this accounts for the strong reason why Jobelyn is a recommended adjunct in the treatment of many diseases including cancer, HIV/AIDS,  Diabetes, Cardiovascular and neurological problems as well as Arthritis.

Jobelyn is being sold through pharmacies throughout Nigeria and also via the internet. You can also purchase directly from the Health Forever store.

For more information on how Jobelyn solves the problem of Oxidative Stress and the related disease conditions such as anemia, cancer, diabetes, rheumatoid arthritis,  cardiovascular diseases, chronic inflammation, stroke, hypertension and kidney disease, inflammation, and tissue damage contact us at:  This email address is being protected from spambots. You need JavaScript enabled to view it.

Website: www.afritradomedic.com

 

 

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STROKE IS PREVENTABLE AND CURABLE

STROKE IS PREVENTABLE AND CURABLE

Stroke attack has become very rampant and it has no age barrier. If it does not result into instant death, it could turn the victim into a vegetable for the rest of his life with the quality of life reduced to almost zero. In some instances, it may give some warning signals but in many other cases, no warning will be given. While browsing on the internet, I stumbled on a publication which is reproduced below:

 “May is National Stroke Awareness month and a time to raise our understanding of the emotional, physical, and financial impact that stroke has on our friends and family”.

A stroke causes a loss of function due to an interruption of blood flow to the brain. Those who suffer a stroke usually experience a number of symptoms, which may include sudden numbness or weakness of the face, arms, or legs—especially on one side of the body; confusion; trouble speaking; loss of sight; severe headaches; and loss of balance. Risk factors include hypertension, high cholesterol, obesity, advanced age, gender, and race.

Stroke affects more than 800,000 people each year and ranks among the five leading causes of death and a leading cause of adult disability in the world. Although a stroke may not be entirely preventable, familiarity with the symptoms of a stroke can prompt you to get help faster, which can make a difference in recovery. Use the acronym FAST to remember the warning signs of a stroke:

 

F - FACE. Ask the person to smile. Does the face appear crooked or drooping?

A - ARMS. Ask the person to raise both arms. Does one arm drift downward?

S - SPEECH. Ask the person to repeat a simple sentence. Are the words slurred?

T - TIME. Call your doctor immediately if you observe any of these symptoms.

 It is important for people to understand stroke warning signs and get to a hospital FAST in case they are eligible to receive the appropriate treatment. Time is an important factor associated with determining whether a patient can receive it or not.”

 A scientist once said that oxidative stress may be at the root of some strokes, as the body may be unable to neutralize cell-damaging free radicals, which can lead to inflammation and vascular damage.

How might antioxidant-rich foods reduce this stroke risk? According to the scientist, vitamins C and E, carotenoids, flavonoids, and other such compounds scavenge free radicals, thereby inhibiting oxidative stress. "Antioxidants, especially flavonoids, may also help improve endothelial function and reduce blood clotting, blood pressure, and inflammation.

How could Stroke be prevented

Eating a healthy, antioxidant rich diet is associated other healthy behaviors. People who tend to eat healthier tend to also have healthier lifestyles as a whole, it is also noteworthy that the diet had an independent beneficial effect on stroke incidence."

The most congruous finding of epidemiologic studies is the lower risk of stroke among individuals with frequent consumption of fruit and vegetables. Eating a diet high in antioxidants may protect against ischemic stroke, an Italian cohort study showed.
Antioxidants come from a variety of food sources, including fruits, vegetables, coffee, chocolate, red wine, whole grain cereals, and nuts, and diets high in antioxidants have been associated with reduced inflammation and increased circulating antioxidants.

One of the newest, and yet oldest, treatments for stroke prevention is the dietary intake of plant compounds called flavonoids. Flavonoids are antioxidant compounds that are characterized by their polyphenolic chemical structure. Flavonoids are responsible for primary anti-oxidative effects by attracting oxygen free radicals before these free radicals can cause cellular damage.

Over 4,000 flavonoids have been discovered, and they are found in fruit, vegetables, seeds, nuts, flowers, and bark. The best sources of flavonoids in human consumables are red wine, tea, onions, and the ubiquitous agent of health care: APPLES! Flavonoids have also been found to aid in vascular smooth muscle relaxation, which can reduce blood pressure, and thereby reduce the risk of stroke.

The use of Jobelyn for the treatment and prevention of Stroke.

Jobelyn is a herbal product derived from Sorghum bicolor. For several centuries, the people of South-Western part of Nigeria have been using this plant in its raw form to treat and cure many diseases including stroke. The impression that I was given that this particular remedy is a cure-all for diseases like Stroke, hypertension, diabetes, arthritis, HIV. Parkinson’s  disease and sickle-cell anemia seemed illogical to me and in an attempt to find out the truth or otherwise, I have set out to carry out scientific investigations over the past 17 years. Our initial focus on the remedy as a blood boosting agent was successful and 2 publications  in the African Journal of Biotechnology in September , 2003 confirmed that our Jobelyn derived from Sorghum bicolor has the potential to be a substitute for blood transfusion except in emergency situation.  This does not give a clue to the cure-all claim of the product until we became aware of the Antioxidant properties of the product. Several studies in the USA and Germany confirmed that Jobelyn is one of the most powerful antioxidants in the world.

A synthetic antioxidant may have the ability to reduce the brain damage following a stroke by more than 40% -- even if it's taken hours after the stroke happens.

A new study shows the antioxidant, known as AEOL 10150, neutralized hazardous free radicals and prevented cell death in a mouse model of stroke. Researchers say the antioxidant is designed to mimic a natural antioxidant, but it works against a wider range of free radicals and also lasts longer in the body.

Naturally occurring antioxidants, such as vitamins C and E, are thought to reduce cell damage within the body by countering the potentially dangerous effects of free radicals produced when the body processes oxygen. Antioxidants are thought to be a promising treatment for strokes because they can be given after a stroke occurs to help reduce cell damage.

Strokes occur when blood flow to the brain is blocked or a blood vessel within the brain ruptures. Brain cells eventually die as they become starved of oxygen, causing paralysis and loss of function. Cell damage can continue hours after a stroke.

In their study, researchers at National Jewish Medical and Research Center and Duke University Medical Center simulated the effects of a stroke in laboratory mice and then injected AEOL 10150 into the brains of the animals six hours after the blocked arteries had been reopened. Researchers say the six-hour time window simulates the amount of time it takes for most stroke victims to receive treatment.

A week later, mice that were given the antioxidant had 43% less brain tissue damage than those who were given a placebo.

Researchers also tested injecting the antioxidant into the veins of the mice rather than directly in the brain. Although this method produced a smaller decrease in brain damage, it reduced both tissue damage and neurological deficit, which means the synthetic antioxidant can move effectively from the blood into the brain.

 Total ORAC FN, short for Total Oxygen Radical Absorbance Capacity for Food and Nutrition, is a laboratory analysis that measures the total antioxidant power of foods and nutritional products.

During April 2009, Brunswick Laboratories, a global leader in antioxidant R&D and testing, introduced its Total ORAC for Food and Nutrition (Total ORAC FN) test. Now patented, Total ORAC FN measures antioxidant activity against five of the most important free radicals found in humans: hydroxyl, peroxyl, peroxynitrite, singlet oxygen and super oxide anion.

Total ORAC FN, considered a breakthrough technology, combines all five measurements into a single, easy to use test result. The original ORAC essay measured only one of the five major radicals, the peroxyl radical, giving an incomplete picture of the antioxidant strength of a product.

The five major free radicals work individually and in combination with each other to cause damage to many systems in the human body and can affect total health. At times, environmental factors such as pollution, radiation, cigarette smoke, UV light, and herbicides can overwhelm the body’s natural ability to fight the free radicals and the damage they cause.

Total ORAC FN allows premium food and nutrition products to be differentiated in the marketplace by providing a single Total ORAC FN "score."  Jobelyn scores 37,622

Having realized the potency of Jobelyn as a powerful antioxidant, we have tried it for the treatment of many diseases including Stroke. For stroke that happens within 24 hours, Jobelyn taken 6 capsules, 4 times daily at intervals of 3 hours and accompanied with daily water intake of at least 3 - 4 litres would reverse the damaging effects of the stroke within a period of 2 – 4 weeks. For stroke that had taken long, the treatment that we have successfully adopted is 4 capsules of Jobelyn, 3 times daily, also with at least 3 – 4 litres of water daily. In this case, reversal or near-complete reversal would be possible within a period of 4 – 6 months.

It is however more advantageous to use Jobelyn to prevent stroke and many other diseases by taking a daily dose of 2 capsules, twice daily. The old adage that prevention is better than cure applies in this case.

There are other aspects of health where Jobelyn has been tried. We have devised a formula for the successful treatment of Arthritis. We recommend that patients take 3 capsules of Jobelyn, 3 times daily, with 3 bottles of water (1.5 litre size) and in three months, the problem should be resolved. We even offer money back guarantee if  the result is not achieved. This formula could also be tried for Diabetes.

Our clinical studies of Jobelyn on HIV has confirmed that it increases the CD4 count very rapidly and improves the general well-being of patients and we are aware that a daily dose of 6 capsules in 3 divided doses is capable of providing the necessary support that would ensure the general well being of patients.

In a similar vein, sickle-cell anaemia patients sustain their health and maintain their general well-being by daily use of 1 capsule both in the morning and evening.

FURTHER RESEARCH FINDINGS ON JOBELYN

Scientist have concluded that inflammation is involved in almost all diseases afflicting the human system and medicinal products that have anti-inflammatory properties have the potential to be useful for treating many diseases.  The recent study done on Jobelyn by MDbioscienses  of the USA  confirmed that Jobelyn works better than ibuprofen for pain alleviation but does not have the side-effects attributable to it.

One of the findings of a recent study carried out at Alcorn State University (USA), was that total flavonoids  in Jobelyn, 870 mic/ml compared with thyme (318) and basil (205). This led to the conclusion, that, as a source of flavonoids, Jobelyn’s flavonoids almost trebled those most orchestrated flavonoids-rich Euro-American herbs.                         

Flavonoids, crystalline substances found in plants, were discovered in 1936 by Nobel Prize winner Szent Gyorgy, a scientist who named this group of compounds Vitamin P, of which many people know so little.

As a matter of fact, most medicinal plants are said to owe their health powers to their flavonoids. That’s why you’ll find on a health store shelf such proprietary products as FLAVONOIDS COMPLEX or ACTIVATED FLAVONOIDS. Sometimes, they are called BIOFLAVONOIDS, to describe bioactivity. Flavonoids have properties which make them antiviral, anti-carcinogenic, that is, anti-cancer, anti-inflammatory, antihistamine and antioxidant. That’s why they have a range of uses in natural medicine such as in histamine induced asthma, arthritis and chromic degenerative disease with free radical damage origins. It is in their use as antioxidants that bioflavonoids  appear most well-known today. In this area, many of them, such Grape Seed Extract and Sorghum bicolor based Jobelyn, are said to be more potent than traditional antioxidant Vitamins C and E put together. They protect LDL cholesterol from oxidation, for example, thereby prevent cholesterol health damage. They sometimes lower total cholesterol count. That’s why nature doctors often advise inclusion of generous amounts of fruits and vegetables in the diet.

Research has proven bioflavonoids good for diabetic retinopathy, a condition in which high blood sugar levels damage nerves of the eye and the retina, impairing vision. They also help varicose veins, to improve blood flow and heal leg cramps. As antiviral agents, flavonoids have been reported to inhibit viruses which cause polio, influenza, hepatitis A and B, herpes simplex, leukemia virus type I and HIV.

Flavonoids for Health

Common flavonoids are quercetin, kaempferol, myricetin, luteolin, and apigenin, which tend to be found in vegetables and fruit. Using fruit and vegetable intake as a measure of flavonoid uptake, it was found that men without strokes had consumed on average 77.2 g per day of solid non-citrus fruit, as compared to high stroke risk men with an intake of 57.4 g per day . It was also found that those in the stroke-free category had also consumed more citrus fruit (vitamin C), more vegetables (beta-carotene, and others), and more tea (other flavonoids). More surprising was that when looking at the sources of flavonoids directly, in the same study, it was learned that 70% of flavonoid intake was on tea alone, and about 10% from apples. (Both black and green teas provide the same amount of dietary flavonoids.) The protective benefits of flavonoids provide the strongest proof for their importance: the men who were stroke-free in the study, who consumed flavonoids in the top quartile of intake, had a 73% less risk of stroke. Flavonoids are beneficial not only for stroke, but in terms of cancer and coronary heart disease prevention, as well, using similar prevention of lipid oxidation mechanisms like vitamin B12 and beta-carotene .

In essence, it is important to look at one’s diet as crucial in stroke prevention, while there are familial risk factors for stroke, one can cut their non-genetic risk in half by simply watching their diet and insuring proper intake of antioxidants and other vitamins. A big concern then is raised with why then shouldn’t we increase our levels of these compounds using pill-style supplementation, rather than eating vegetables and fruits and maintaining adequate overall

vitamin intakes. As we saw in the case of vitamin E and beta-carotene, large doses of betacarotene can actually increase one’s risk for stroke since large doses of beta-carotene can deplete the body of vitamin E . Obviously, in compounds such as vitamin B12, which is primarily from fortified foods and from endogenous sources such as enteric bacteria, it is important to look for foods high in vitamin B12. Obviously, in patients with intrinsic factor deficiency, both forms of supplementation will prove insufficient, and other means of increasing vitamin B12 are necessary. Most importantly, we know so little in respect to the flavonoids and other phytocompounds of fruit and vegetable origin and their systemic effects, that there are many great, but undiscovered benefits of eating large quantities of them. Lastly, fruits and vegetables serve as sources of fiber, which will have a too fold effect: 1) By allowing for the "fullness" feeling after eating, they will prevent eating more than necessary, and can help to reduce fat intake, and are great snacks. For those with chronic hemorrhoids, dietary fiber can soften stool and prevent many common causes of hemorrhoids. Fiber also helps to reduce cholesterol levels, since it can reduce fat intake, and by the same mechanism can promote better health, preventing atherosclerosis . There are great benefits to these treatments in addition to just stroke prevention with these vitamin and antioxidant supplements. Coronary Artery Disease (CAD), ischemic heart disease, and cancers of free-radical mutagenic origin can be greatly prevented using similar measures of increasing intake of these antioxidants . Since stroke is a definitively predictable illness for 550,000 Americans, if we watch what we eat, and have a bit more fruit and vegetables in our diet, we can spare ourselves many of the problems associated with stroke. Remember: A diet with apples, oranges, more fruit and more vegetables a day will keep the neurosurgeon away.

CONCLUSION

 In concluding this piece, it is necessary to emphasise that a healthy diet which includes regular consumption of fruits and vegetables would prevent many serious diseases but we need to state that a powerful antioxidant like Jobelyn, concentrated in capsules could as well prevent you from diseases and taken at a higher dosage could also reverse diseases and help you to maintain your wellness.

 

 

 

 

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